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Theophylline

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Theophylline

Theophylline

Theophylline is a naturally occurring methylxanthine derivative used primarily as a bronchodilator. It relaxes the smooth muscles of the airways, making it easier to breathe, and is commonly used to treat asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). Theophylline also has mild cardiac stimulant and diuretic effects and is included in the WHO Model List of Essential Medicines for respiratory diseases.

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Description

🔹 Key Details:

  • Chemical Name: 1,3-Dimethylxanthine
  • CAS Number: 58-55-9
  • Molecular Formula: C₇H₈N₄O₂
  • Molecular Weight: 180.16 g/mol
  • Appearance: White to slightly yellow crystalline powder
  • Melting Point: ~270–274°C (with decomposition)
  • Solubility: Slightly soluble in water; more soluble in hot water and organic solvents
  • Pharmacopoeia Standards: USP, BP, EP, IP

 

🔹 Applications:

  • Therapeutic Use: Long-term control of asthma symptoms and prevention of nighttime asthma attacks; sometimes used for COPD

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