Petalheadexim

Cetirizine Dihydrochloride

Cetirizine Dihydrochloride

Cetirizine Dihydrochloride is the dihydrochloride salt form of cetirizine, a second-generation, non-sedating H1-antihistamine. It is used to relieve allergy symptoms such as sneezing, runny nose, itchy eyes, and hives by blocking histamine receptors. Cetirizine Dihydrochloride is favored for its once-daily dosing, minimal sedation.

Inquiry
Category:

Description

🔹 Key Details:

  • Chemical Name: (±)-2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride
  • CAS Number: 163837-48-7
  • Molecular Formula: C₂₁H₂₅ClN₂O₃·2HCl
  • Molecular Weight: 461.81 g/mol
  • Appearance: White to off-white crystalline powder
  • Melting Point: ~110–115°C
  • Solubility: Freely soluble in water and methanol
  • Storage: Store in a cool, dry place; protected from light
  • Pharmacopoeia Standards: Complies with USP/EP/BP

 

🔹 Applications:

  • Therapeutic Use:
  • Allergic rhinitis (seasonal/perennial)
  • Chronic idiopathic urticaria (hives)